Article
Female premenopausal fracture risk is associated with gc phenotype.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Jun 2004
Lauridsen Anna Lis, Vestergaard Peter, Hermann Anne Pernille, Moller Holger Jon, Mosekilde Leif, Nexo Ebba
Abstract excerpt
UNLABELLED: The phenotype of the vitamin D binding and macrophage activating protein, Gc, is a predictor of premenopausal bone fracture risk, possibly mediated through activation of osteoclasts. This was concluded from a study on 595 Danish perimenopausal women 45-58 years of age (30,040 person years). INTRODUCTION: The multifunctional plasma protein Gc, also known as group-specific component, Gc globulin, or...
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