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Article

Vitamin D binding protein genotype is associated with serum 25-hydroxyvitamin D and PTH concentrations, as well as bone health in children and adolescents in Finland.

PloS one - 1 Jan 2014

Pekkinen Minna, Saarnio Elisa, Viljakainen Heli T, Kokkonen Elina, Jakobsen Jette, Cashman Kevin, Mäkitie Outi, Lamberg-Allardt Christel

Abstract excerpt

Vitamin D binding protein (DBP)/group-specific component (Gc), correlates positively with serum vitamin D metabolites, and phenotype influences serum 25-hydroxyvitamin D (S-25(OH)D) concentration. The protein isoform has been associated with decreased bone mineral density (BMD) and increased fracture risk. We examined the role of GC genotypes in S-25(OH)D status and BMD in 231 Finnish children and adolescents...

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Source

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Identifiers

PMID: 24498064
DOI: 10.1371/journal.pone.0087292
PMCID: PMC3907502

Genes

PTH
DBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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