Article
Vitamin D binding protein genotype and osteoporosis.
Calcified tissue international - 1 Aug 2009
Fang Yue, van Meurs Joyce B J, Arp Pascal, van Leeuwen Johannes P T, Hofman Albert, Pols Huibert A P, Uitterlinden André G
Abstract excerpt
Osteoporosis is a bone disease leading to an increased fracture risk. It is considered a complex multifactorial genetic disorder with interaction of environmental and genetic factors. As a candidate gene for osteoporosis, we studied vitamin D binding protein (DBP, or group-specific component, Gc), which binds to and transports vitamin D to target tissues to maintain calcium homeostasis through the vitamin D...
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