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Article

The DBP Phenotype Gc-1f/Gc-1f Is Associated with Reduced Risk of Cancer. The Tromsø Study.

PloS one - 1 Jan 2015

Jorde Rolf, Schirmer Henrik, Wilsgaard Tom, Bøgeberg Mathiesen Ellisiv, Njølstad Inger, Løchen Maja-Lisa, Joakimsen Ragnar Martin, Grimnes Guri

Abstract excerpt

BACKGROUND AND OBJECTIVE: In addition to its role as a transport protein, the vitamin D binding protein (DBP) may also affect lipid metabolism, inflammation and carcinogenesis. There are three common variants of the DBP, Gc1s (1s), Gc1f (1f), Gc2 (2) that result in six common phenotypes (1s/1s, 1s/1f, 1s/2, 1f/1f, 1f/2, and 2/2). These phenotypes can be identified by genotyping for the two single nucleotide...

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Identifiers

PMID: 25993554
DOI: 10.1371/journal.pone.0126359
PMCID: PMC4436319

Genes

DBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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