Article
Apolipoprotein E genotype does not influence the progression of multiple sclerosis.
Journal of neurology - 1 Sept 2003
Savettieri Giovanni, Andreoli Virginia, Bonavita Simona, Cittadella Rita, Caltagirone Carlo, Fazio Maria Carolina, Girlanda Paolo, Le Pira Francesco, Liguori Maria, Logroscino Giancarlo, Lugaresi Alessandra, Nocentini Ugo, Reggio Arturo, Salemi Giuseppe, Serra Paolo, Tedeschi Gioacchino, Toma Lucia, Trojano Maria, Valentino Paola, Quattrone Aldo
Abstract excerpt
OBJECTIVE: To investigate the association between apolipoprotein E (APOE) polymorphisms and the progression of MS. METHODS: We investigated 428 subjects affected by clinically defined MS, with a disease duration of at least three years. We collected data concerning the age at onset of MS, clinical type, disease duration and disability according to the expanded disability status scale (EDSS). We also calculated...
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