Article
Connexin43 pseudogene is expressed in tumor cells and inhibits growth.
Oncogene - 10 Jun 2004
Kandouz Mustapha, Bier Andrew, Carystinos George D, Alaoui-Jamali Moulay A, Batist Gerald
Abstract excerpt
Pseudogenes are classically thought of as nonfunctional DNA sequences due to their inability to be translated, or to produce a functional protein. Gap junctions, a multiprotein complex made of proteins called connexins, are involved in intercellular communication and are deregulated in many cancers. Connexin43 (Cx43) is the only connexin for which a pseudogene has been reported so far. The Cx43 pseudogene...
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