Role of CtBP in transcriptional repression by the Drosophila giant protein.

doi:10.1006/dbio.2001.0454

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Article

Role of CtBP in transcriptional repression by the Drosophila giant protein.

Developmental biology - 15 Nov 2001

Strunk B, Struffi P, Wright K, Pabst B, Thomas J, Qin L, Arnosti D N

Abstract excerpt

The giant protein is a short-range transcriptional repressor that refines the expression pattern of gap and pair-rule genes in the Drosophila blastoderm embryo. Short-range repressors including knirps, Krüppel, and snail utilize the CtBP cofactor for repression, but it is not known whether a functional interaction with CtBP is a general property of all short-range repressors. We studied giant repression activity...

Topics

Alcohol Oxidoreductases
Amino Acid Motifs
Amino Acid Sequence
Animals
Base Sequence
Conserved Sequence
DNA-Binding Proteins
Drosophila
Drosophila Proteins
Enhancer Elements, Genetic
Gene Expression Regulation, Developmental

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genes, Reporter

In Situ Hybridization

Lac Operon

Molecular Sequence Data

Mutation

Phosphoproteins

Plasmids

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Identifiers

PMID: 11784031
DOI: 10.1006/dbio.2001.0454

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