Article
Role of CtBP in transcriptional repression by the Drosophila giant protein.
Developmental biology - 15 Nov 2001
Strunk B, Struffi P, Wright K, Pabst B, Thomas J, Qin L, Arnosti D N
Abstract excerpt
The giant protein is a short-range transcriptional repressor that refines the expression pattern of gap and pair-rule genes in the Drosophila blastoderm embryo. Short-range repressors including knirps, Krüppel, and snail utilize the CtBP cofactor for repression, but it is not known whether a functional interaction with CtBP is a general property of all short-range repressors. We studied giant repression activity...
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