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Article

Identification of PIK3C3 promoter variant associated with bipolar disorder and schizophrenia.

Biological psychiatry - 15 May 2004

Stopkova Pavla, Saito Takuya, Papolos Demitri F, Vevera Jan, Paclt Ivo, Zukov Ilja, Bersson Yonina B, Margolis Benjamin A, Strous Rael D, Lachman Herbert M

Abstract excerpt

BACKGROUND: Genes involved in phosphoinositide (PI) lipid metabolism are excellent candidates to consider in the pathogenesis of bipolar disorder (BD) and schizophrenia (SZ). One is PIK3C3, a member of the phosphatidylinositide 3-kinase family that maps closely to markers on 18q linked to both BD and SZ in a few studies. METHODS: The promoter region of PIK3C3 was analyzed for mutations by single-strand...

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PMID: 15121481
DOI: 10.1016/j.biopsych.2004.01.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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