Article
A case-control association study and family-based expression analysis of the bipolar disorder candidate gene PI4K2B.
Journal of psychiatric research - 1 Dec 2009
Houlihan Lorna M, Christoforou Andrea, Arbuckle Margaret I, Torrance Helen S, Anderson Susan M, Muir Walter J, Porteous David J, Blackwood Douglas H, Evans Kathryn L
Abstract excerpt
Bipolar disorder, schizophrenia and recurrent major depression are complex psychiatric illnesses with a substantial, yet unknown genetic component. Linkage of bipolar disorder and recurrent major depression with markers on chromosome 4p15-p16 has been identified in a large Scottish family and three smaller families. Analysis of haplotypes in the four chromosome 4p-linked families, identified two regions, each...
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