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Article

IL-22, a Th1 cytokine that targets the pancreas and select other peripheral tissues.

International immunopharmacology - 1 May 2004

Gurney Austin L

Abstract excerpt

IL-22, also termed IL-TIF, is a member of the IL-10 family of cytokines. Its principal source appears to be memory CD4 T cells with a Th1 polarized phenotype. IL-22 induces its signals through a two-component receptor comprised of IL-22R1 and CRF2-4/IL10Rb. Both of these receptor components also participate in separate receptor complexes specific for other IL-10 family cytokines. Because CRF2-4 exhibits...

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Identifiers

PMID: 15120651
DOI: 10.1016/j.intimp.2004.01.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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