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IL-22 Binding Protein (IL-22BP) in the Regulation of IL-22 Biology

15 Nov 2021

Abstract excerpt

Cytokines are powerful mediators of inflammation. Consequently, their potency is regulated in many ways to protect the host. Several cytokines, including IL-22, have coordinating binding proteins or soluble receptors that bind to the cytokine, block the interaction with the cellular receptor, and thus prevent cellular signaling. IL-22 is a critical cytokine in the modulation of tissue responses during...

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PMID: 34868019
DOI: 10.3389/fimmu.2021.766586

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