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Article

The biology of IL-12: coordinating innate and adaptive immune responses.

Cytokine & growth factor reviews - 1 Oct 2003

Watford Wendy T, Moriguchi Masato, Morinobu Akio, O'Shea John J

Abstract excerpt

Cytokines play critical roles in regulating all aspects of immune responses, including lymphoid development, homeostasis, differentiation, tolerance and memory. Interleukin (IL)-12 is especially important because its expression during infection regulates innate responses and determines the type and duration of adaptive immune response. IL-12 induces interferon-gamma (IFN-gamma) production by NK, T cells,...

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Source

Identifiers

PMID: 12948519
DOI: 10.1016/s1359-6101(03)00043-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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