Article
Tbx12 regulates eye development in Xenopus embryos.
Biochemical and biophysical research communications - 28 May 2004
Carson Christian T, Pagratis Maria, Parr Brian A
Abstract excerpt
The regulation of vertebrate eye development requires the activity of many transcription factors. In this report, we demonstrate that the T-box factor Tbx12 is necessary for normal development of the retina. Tbx12 is expressed during early stages of retinal development in multiple species of vertebrate embryos. We injected mRNAs encoding wild type and mutant forms of Tbx12 into Xenopus embryos. The Tbx12 injected...
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