Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prognostic Value of Proliferation, Apoptosis, Defective DNA Mismatch Repair, and p53 Overexpression in Patients With Resected Dukes' B2 or C Colon Cancer

29 Apr 2004

Abstract excerpt

PURPOSE: Molecular studies of colon cancer have provided insights into pathogenesis, yet it is unclear how important these markers are in predicting prognosis. This study investigated the prognostic significance of TUNEL, bcl-2, p53, proliferation marker Ki-67 and DNA mismatch repair (MMR) status in patients with Dukes' stage B2 and C colorectal adenocarcinomas. PATIENTS AND METHODS: Tumor tissue from 366...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Colorectal Cancer Surgical Treatments
Share to Colorectal Cancer Treatments and Studies
Share to Genetic factors in colorectal cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15117979
DOI: 10.1200/jco.2004.10.042

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prognostic Value of Proliferation, Apoptosis, Defective DNA Mismatch Repair, and p53 Overexpression in Patients With Resected Dukes' B2 or C Colon CancerPMID 15117979Read ↗

Analysis of apoptosis protein expression in early-stage colorectal cancer suggests opportunities for new prognostic biomarkers.Semantic proximity Read ↗

Histopathological grade, mucinous differentiation and DNA ploidy in relation to prognosis in colorectal carcinomaSemantic proximity Read ↗

p53 alterations are associated with improved prognosis in distal colonic carcinomas.Semantic proximity Read ↗

Studies on p53, BAX and Bcl-2 protein expression and microsatellite instability in stage III (UICC) colon cancer treated by adjuvant chemotherapy: major prognostic impact of proapoptotic BAXSemantic proximity Read ↗

TP53 Mutational Status and Prediction of Benefit from Adjuvant 5-Fluorouracil in Stage III Colon Cancer Patients.Semantic proximity Read ↗

p53 and Ki-ras as prognostic factors for Dukes' stage B colorectal cancer.Semantic proximity Read ↗

Quantitative expression analysis and prognostic significance of the novel apoptosis-related gene <i>BCL2L12</i> in colon cancerSemantic proximity Read ↗

Current status of adjuvant chemotherapy for colorectal cancer. Can molecular markers play a role in predicting prognosis?Semantic proximity Read ↗

Mutated p53 gene is an independent adverse predictor of survival in colon carcinoma.Semantic proximity Read ↗

Molecular staging of colorectal cancer: K-ras mutation analysis of lymph nodes upstages Dukes B patients.Semantic proximity Read ↗

Immunohistochemical detection of mutant p53 protein in regional lymph nodes is associated with adverse outcome in stage II colorectal cancer.Semantic proximity Read ↗

Prognostic value of p53 overexpression and c-Ki-ras gene mutations in colorectal cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.