Article
Mutated p53 gene is an independent adverse predictor of survival in colon carcinoma.
Archives of surgery (Chicago, Ill. : 1960) - 1 Apr 1997
Pricolo V E, Finkelstein S D, Hansen K, Cole B F, Bland K I
Abstract excerpt
OBJECTIVE: To evaluate the impact of p53 gene mutations on long-term survival in patients with intermediate stage carcinoma of the colon. DESIGN: Retrospective cohort study; median follow-up of 87 months. SETTING: Tertiary care academic medical center. PATIENTS: Mutational analysis was conducted in a single institution in 141 consecutive patients with resected stage II (n = 71) and stage III (n = 70) colon...
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