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Article

HCMV Reprogramming of Infected Monocyte Survival and Differentiation: A Goldilocks Phenomenon

13 Feb 2014

Abstract excerpt

The wide range of disease pathologies seen in multiple organ sites associated with human cytomegalovirus (HCMV) infection results from the systemic hematogenous dissemination of the virus, which is mediated predominately by infected monocytes. In addition to their role in viral spread, infected monocytes are also known to play a key role in viral latency and life-long persistence. However, in order to utilize...

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PMID: 24531335
DOI: 10.3390/v6020782

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