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Macrophages and their relevance in Human Immunodeficiency Virus Type I infection

4 Oct 2012

Abstract excerpt

Macrophages are important target cells for the Human Immunodeficiency Virus Type I (HIV-1) in vivo. Several studies have assessed the molecular biology of the virus in this cell type, and a number of differences towards HIV-1 infection of CD4+ T cells have been described. There is a broad consensus that macrophages resist HIV-1 infection much better than CD4+ T cells. Among other reasons, this is due to the...

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PMID: 23035819
DOI: 10.1186/1742-4690-9-82

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