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Article

HIV-1 Latency in Monocytes/Macrophages

22 Apr 2014

Abstract excerpt

Human immunodeficiency virus type 1 (HIV-1) targets CD4+ T cells and cells of the monocyte/macrophage lineage. HIV pathogenesis is characterized by the depletion of T lymphocytes and by the presence of a population of cells in which latency has been established called the HIV-1 reservoir. Highly active antiretroviral therapy (HAART) has significantly improved the life of HIV-1 infected patients. However, complete...

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PMID: 24759213
DOI: 10.3390/v6041837

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