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Article

Structural and functional roles of desmin in mouse skeletal muscle during passive deformation.

Biophysical journal - 1 May 2004

Shah Sameer B, Davis Jennifer, Weisleder Noah, Kostavassili Ioanna, McCulloch Andrew D, Ralston Evelyn, Capetanaki Yassemi, Lieber Richard L

Abstract excerpt

Mechanical interactions between desmin and Z-disks, costameres, and nuclei were measured during passive deformation of single muscle cells. Image processing and continuum kinematics were used to quantify the structural connectivity among these structures. Analysis of both wild-type and desmin-null fibers revealed that the costamere protein talin colocalized with the Z-disk protein alpha-actinin, even at very high...

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Identifiers

PMID: 15111414
DOI: 10.1016/S0006-3495(04)74349-0
PMCID: PMC1304166

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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