Article
Ipsilateral breast tumour recurrence in hereditary breast cancer following breast-conserving therapy.
European journal of cancer (Oxford, England : 1990) - 1 May 2004
Seynaeve C, Verhoog L C, van de Bosch L M C, van Geel A N, Menke-Pluymers M, Meijers-Heijboer E J, van den Ouweland A M W, Wagner A, Creutzberg C L, Niermeijer M F, Klijn J G M, Brekelmans C T M
Abstract excerpt
The overall rate of an ipsilateral breast tumour recurrence (IBTR) after breast-conserving therapy (BCT) ranges from 1% to 2% per year. Risk factors include young age but data on the impact of BRCA1/2 mutations or a definite positive family history for breast cancer are scarce. We investigated IBTR after BCT in patients with hereditary breast cancer (HBC). Through our family cancer clinic we identified 87 HBC...
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