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Article

High risk of in-breast tumor recurrence after BRCA1/2-associated breast cancer.

Breast cancer research and treatment - 1 Oct 2014

Nilsson Martin P, Hartman Linda, Kristoffersson Ulf, Johannsson Oskar T, Borg Ake, Henriksson Karin, Lanke Elsa, Olsson Håkan, Loman Niklas

Abstract excerpt

The purpose of the study was to compare breast-conserving therapy (BCT) and mastectomy (M) in BRCA1/2 mutation carriers. Women with invasive breast cancer and a pathogenic mutation in BRCA1 or BRCA2 were included in the study (n = 162). Patients treated with BCT (n = 45) were compared with patients treated with M (n = 118). Endpoints were local recurrence as first recurrence (LR), overall survival (OS), breast...

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Identifiers

PMID: 25187270
DOI: 10.1007/s10549-014-3115-3
PMCID: PMC4174291

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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