Article
Contralateral breast cancer and tumor recurrence in BRCA1/2 carriers and non-carriers at a high risk of hereditary breast cancer after bilateral mastectomy.
Cirugia espanola - 1 Dec 2020
Allué Cabañuz Marta, Domingo Bretón María, Chóliz Ezquerro Jorge, Arribas Del Amo María Dolores, Güemes Sánchez Antonio Tomás
Abstract excerpt
INTRODUCTION: Contralateral prophylactic mastectomy (CPM) has been reported to reduce risk of contralateral breast cancer (CBC) by at least 90%.In addition, BRCA carriers presents higher risk of ipsilateral recurrence and a second primary tumor. The aim is to evaluate risk of CBC and recurrence and to analyze predictive factors in BRCA1/2 mutation carriers and non-carriers at high-risk of hereditary breast cancer...
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