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Article

DNMT3L Stimulates the DNA Methylation Activity of Dnmt3a and Dnmt3b through a Direct Interaction

1 Jun 2004

Abstract excerpt

In mammals, the resetting of DNA methylation patterns in early embryos and germ cells is crucial for development. Two DNA methyltransferases, Dnmt3a and Dnmt3b, are responsible for the creation of DNA methylation patterns. Dnmt3L, a member of the Dnmt3 family, has been reported to be necessary for maternal methylation imprinting, possibly by interacting with Dnmt3a and/or Dnmt3b (Hata, K., Okano, M., Lei, H., and...

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Share to Epigenetics and DNA Methylation
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Identifiers

PMID: 15105426
DOI: 10.1074/jbc.m400181200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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DNMT3L Stimulates the DNA Methylation Activity of Dnmt3a and Dnmt3b through a Direct InteractionPMID 15105426Read ↗

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