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Article

LuxS is required for persistent pneumococcal carriage and expression of virulence and biosynthesis genes.

Infection and immunity - 1 May 2004

Joyce Elizabeth A, Kawale Amita, Censini Stefano, Kim Charles C, Covacci Antonello, Falkow Stanley

Abstract excerpt

Streptococcus pneumoniae causes several diseases, including otitis media, pneumonia, and meningitis. Although little is known about the regulation of or how individual pneumococcal factors contribute to these disease states, there is evidence suggesting that some factors are regulated by a cell-density-dependent mechanism (quorum sensing). Quorum sensing allows bacteria to couple transcription with changes in...

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Identifiers

PMID: 15102809
DOI: 10.1128/IAI.72.5.2964-2975.2004
PMCID: PMC387900

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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