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Article

Role of two-component systems in the virulence of Streptococcus pneumoniae

13 Mar 2006

Abstract excerpt

Understanding of how the human pathogen Streptococcus pneumoniae perceives and responds to its environment in the host offers insight into the pathogenesis of disease caused by this important bacterium and the potential for improved interventions. A central role in this environmental response is played by two-component systems (TCSs), which both sense the environment and drive the cellular response. Molecular...

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PMID: 16533981
DOI: 10.1099/jmm.0.46423-0

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