Article
Microarray analysis of pneumococcal gene expression during invasive disease.
Infection and immunity - 1 Oct 2004
Orihuela Carlos J, Radin Jana N, Sublett Jack E, Gao Geli, Kaushal Deepak, Tuomanen Elaine I
Abstract excerpt
Streptococcus pneumoniae is a leading cause of invasive bacterial disease. This is the first study to examine the expression of S. pneumoniae genes in vivo by using whole-genome microarrays available from The Institute for Genomic Research. Total RNA was collected from pneumococci isolated from infected blood, infected cerebrospinal fluid, and bacteria attached to a pharyngeal epithelial cell line in vitro....
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