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Article

Investigation of LuxS-mediated quorum sensing in Klebsiella pneumoniae.

Journal of medical microbiology - 1 Mar 2020

Chen Lijiang, Wilksch Jonathan J, Liu Haiyang, Zhang Xiaoxiao, Torres Von V L, Bi Wenzi, Mandela Eric, Cao Jianming, Li Jiahui, Lithgow Trevor, Zhou Tieli

Abstract excerpt

Introduction. Autoinducer-2 (AI-2) quorum sensing is a bacterial communication system that responds to cell density. The system requires luxS activity to produce AI-2, which can regulate gene expression and processes such as biofilm formation.Aim. To investigate the role of luxS in biofilm formation and gene expression in the nosocomial pathogen Klebsiella pneumoniae.Methodology. A ΔluxS gene deletion was made...

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Identifiers

PMID: 32223838
DOI: 10.1099/jmm.0.001148
PMCID: PMC7377169

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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