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Article

Effect of beta2-glycoprotein I null mutation on reproductive outcome and antiphospholipid antibody-mediated pregnancy pathology in mice.

Molecular human reproduction - 1 Jun 2004

Robertson Sarah A, Roberts Claire T, van Beijering Eline, Pensa Katherine, Sheng Yonghua, Shi Tong, Krilis Steven A

Abstract excerpt

beta(2)-Glycoprotein I (beta(2)GPI) is a principal target antigen for antiphospholipid antibodies associated with recurrent pregnancy loss and fetal growth restriction in women. The significance of disrupted beta(2)GPI activity in contributing to pregnancy pathology in antiphospholipid syndrome (APS) is not clear. In this study the physiological requirement for functional beta(2)GPI in pregnancy was investigated...

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Source

Identifiers

PMID: 15100383
DOI: 10.1093/molehr/gah058

Genes

GPI

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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