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Understanding the structure of β2-glycoprotein I: new insights and future paths for antiphospholipid syndrome

24 Dec 2024

Abstract excerpt

Antiphospholipid syndrome (APS) is an autoimmune disorder characterized by recurrent life-threatening blood clots and pregnancy complications in individuals with antiphospholipid antibodies. Among these antibodies, those targeting the plasma glycoprotein β 2 -glycoprotein I (β 2 GPI) hold particular clinical significance. Despite extensive research, controversies persist regarding the structure of β 2 GPI, which...

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PMID: 40766279
DOI: 10.1016/j.bvth.2024.100041

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