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Article

Epithelioid rhabdomyosarcoma: a clinicopathologic and molecular study.

The American journal of surgical pathology - 1 Feb 2014

Zin Angelica, Bertorelle Roberta, Dall'Igna Patrizia, Manzitti Carla, Gambini Claudio, Bisogno Gianni, Rosolen Angelo, Alaggio Rita

Abstract excerpt

Rhabdomyosarcoma (RMS) is the most common pediatric soft tissue sarcoma and is mostly represented by the embryonal (ERMS) and alveolar (ARMS) histotypes. Whereas ERMS shows variable genetic alterations including TP53, RB1, and RAS mutations, ARMS carries a gene fusion between PAX3 or PAX7 and FOXO1. Epithelioid RMS is a morphologic variant of RMS recently described in adults. Five cases of epithelioid RMS were...

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Source

Identifiers

PMID: 24418861
DOI: 10.1097/PAS.0000000000000105

Genes

FOXO1
PAX3
PAX7

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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