Article
Genetic and phenotypic analysis of biofilm phenotypic variation in multiple Staphylococcus epidermidis isolates.
Journal of medical microbiology - 1 May 2004
Handke L D, Conlon K M, Slater S R, Elbaruni S, Fitzpatrick F, Humphreys H, Giles W P, Rupp M E, Fey P D, O'Gara J P
Abstract excerpt
Production of biofilm in Staphylococcus epidermidis is mediated through enzymes produced by the four-gene operon ica and is subject to phenotypic variation. The purpose of these experiments was to investigate the regulation of ica and icaR transcription in phenotypic variants produced by multiple unrelated isolates of S. epidermidis. Ten isolates were chosen for the study, four of which contained IS256. IS256...
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