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Article

The two-component signal transduction system ArlRS regulates Staphylococcus epidermidis biofilm formation in an ica-dependent manner.

PloS one - 1 Jan 2012

Wu Yang, Wang Jiaxue, Xu Tao, Liu Jingran, Yu Wenqi, Lou Qiang, Zhu Tao, He Nianan, Ben Haijing, Hu Jian, Götz Friedrich, Qu Di

Abstract excerpt

Due to its ability to form biofilms on medical devices, Staphylococcus epidermidis has emerged as a major pathogen of nosocomial infections. In this study, we investigated the role of the two-component signal transduction system ArlRS in regulating S. epidermidis biofilm formation. An ArlRS-deficient mutant, WW06, was constructed using S. epidermidis strain 1457 as a parental strain. Although the growth curve of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22848368
DOI: 10.1371/journal.pone.0040041
PMCID: PMC3407220

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