Article
Formation and properties of in vitro biofilms of ica-negative Staphylococcus epidermidis clinical isolates.
Journal of medical microbiology - 1 Jan 2007
Qin Zhiqiang, Yang Xiaomei, Yang Lei, Jiang Juan, Ou Yuanzhu, Molin Soeren, Qu Di
Abstract excerpt
Coagulase-negative Staphylococcus epidermidis has become the leading cause of foreign-body infections due to its biofilm formation on all kinds of medical-device surfaces. The biofilm development of S. epidermidis includes two steps: the initial attachment phase and the accumulative phase. In the accumulative phase, the polysaccharide intercellular adhesin (PIA), encoded by the icaADBC locus, is the major...
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