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Article

Glycosphingolipids govern gene expression.

Glycoconjugate journal - 1 Jan 2004

Inokuchi Jin-ichi, Kabayama Kazuya, Uemura Satoshi, Igarashi Yasuyuki

Abstract excerpt

To elucidate the biological significance of the lactosylceramide (LacCer) branching in glycosphingolipid (GSL) biosynthesis, we established ganglioside GM3- and lactosylsulfatide SM3-reconstituted cells by introducing the GM3 synthase gene and the sulfotransferase gene, respectively. In SM3-expressing cells, the reduction of beta1 integrin mRNA expression, the reduced adhesivity to fibronectin and laminin, and...

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Identifiers

PMID: 15090730
DOI: 10.1023/B:GLYC.0000024248.62242.1f

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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