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Article

Differential enhancing effects of alpha2,8-sialyltransferase on the cell proliferation and mobility.

International journal of oncology - 1 Feb 2005

Kamimura Yutaka, Furukawa Keiko, Kittaka Daiji, Nishio Masashi, Hamamura Kazunori, Fukumoto Satoshi, Furukawa Koichi

Abstract excerpt

alpha2,8-Sialyltransferase (alpha2,8S-T, GD3 synthase) has been reported to be involved in the enhanced cell proliferation of malignant tumors. Using a cloned cDNA of alpha2,8S-T, transfectant cells were established and the effects of the gene expression on the cell phenotypes were analyzed. In contrast with PC12 cells, in which we reported marked growth enhancement based on the transfection of alpha2,8S-T,...

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PMID: 15645117

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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