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Article

Expression Cloning and Functional Characterization of Human cDNA for Ganglioside GM3 Synthase

1 Nov 1998

Abstract excerpt

Ganglioside GM3 is a major glycosphingolipid in the plasma membrane and is widely distributed in vertebrates. We describe here the isolation of a human cDNA whose protein product is responsible for the synthesis of GM3. The cloned cDNA spanned 2,359 base pairs, with an open reading frame encoding a protein of 362 amino acids with a predicted molecular mass of 41.7 kDa. The deduced primary structure shows features...

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PMID: 9822625
DOI: 10.1074/jbc.273.48.31652

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