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Article

Genetic mechanisms for the synthesis of fucosyl GM1 in small cell lung cancer cell lines.

Glycobiology - 1 Oct 2006

Tokuda Noriyo, Zhang Qing, Yoshida Shoko, Kusunoki Susumu, Urano Takeshi, Furukawa Keiko, Furukawa Koichi

Abstract excerpt

Fucosyl GM1 has been reported to be specifically expressed in small cell lung cancer (SCLC) cells. However, the genetic basis for the synthesis of fucosyl GM1 has not been investigated. We analyzed the glycosyltransferases responsible for the synthesis of fucosyl GM1 in SCLC cell lines. In four SCLC cell lines expressing fucosyl GM1, both FUT1 and FUT2 mRNAs were detected, indicating that either one or both of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16880505
DOI: 10.1093/glycob/cwl022

Genes

FUT1
FUT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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