Article
Evidence that RNA editing modulates splice site selection in the 5-HT2C receptor gene.
Nucleic acids research - 1 Jan 2004
Flomen Rachel, Knight Joanne, Sham Pak, Kerwin Robert, Makoff Andrew
Abstract excerpt
Adenosine to inosine editing of mRNA from the human 5-HT2C receptor gene (HTR2C) occurs at five exonic positions (A-E) in a stable stem-loop that includes the normal 5' splice site of intron 5 and is flanked by two alternative splice sites. Using in vitro editing, we identified a novel editing si...
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