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Article

Altered RNA editing of serotonin 2C receptor in a rat model of depression.

Neuroscience research - 1 Sept 2005

Iwamoto Kazuya, Nakatani Noriaki, Bundo Miki, Yoshikawa Takeo, Kato Tadafumi

Abstract excerpt

Altered RNA editing of serotonin 2C receptor (HTR2C) has been suggested to be involved in the pathophysiology of major depression. Here we examined RNA editing status of HTR2C in the learned helplessness (LH) rats, one of well-established animal models of depression. LH rats showed the significantly increased RNA editing of site E, and tendency for increased RNA editing of other editing sites. Treatment with...

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Share to Adenosine Deaminase
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Rats, Sprague-Dawley

Share to Receptor, Serotonin, 5-HT2C

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Source

Identifiers

PMID: 16005997
DOI: 10.1016/j.neures.2005.06.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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