Article
Modulation of apelin and APJ receptor in normal and preeclampsia-complicated placentas.
1 Jan 2007
Abstract excerpt
Apelin is an endogenous ligand of the human orphan receptor APJ. This peptide is produced through processing from the C-terminal portion in the pre-pro-protein consisting of 77 amino acid residues and exists in multiple molecular forms. Although the main physiological functions of apelin have not yet been clarified, it is known that apelin is involved in the regulation of blood pressure, blood flow and central...
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