Article
PPAR-gamma gene polymorphisms and psoriatic arthritis.
The Journal of rheumatology - 1 Aug 2006
Butt Christopher, Gladman Dafna, Rahman Proton
Abstract excerpt
OBJECTIVE: Peroxisome proliferator-activated receptor-gamma (PPAR-gamma) activation has been shown to play a role in suppressing angiogenesis and inflammation, both important pathological features of psoriatic arthritis (PsA). Given the potential physiological role for PPAR-gamma in PsA, we examined known coding polymorphisms in the PPAR-gamma gene in a Caucasian population. METHODS: PsA was diagnosed as an...
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