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Article

Analysis of PPARγ Signaling Activity in Psoriasis

10 Aug 2021

Abstract excerpt

In our previous work, we built the model of PPARγ dependent pathways involved in the development of the psoriatic lesions. Peroxisome proliferator-activated receptor gamma (PPARγ) is a nuclear receptor and transcription factor which regulates the expression of many proinflammatory genes. We tested the hypothesis that low levels of PPARγ expression promote the development of psoriatic lesions triggering the...

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PMID: 34445309
DOI: 10.3390/ijms22168603

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