Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

p150Sal2 Is a p53-Independent Regulator of p21WAF1/CIP

13 Apr 2004

Abstract excerpt

p150(Sal2), a vertebrate homologue of the Drosophila melanogaster homeotic transcription factor Spalt, has previously been shown to be a binding target of the polyomavirus large T antigen. p150(Sal2) acts as an inhibitor of viral DNA synthesis, and the binding of p150(Sal2) by large T overcomes this inhibition. The present study focuses on the effects of p150(Sal2) on the growth and survival of ovarian carcinoma...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related gene regulation
Share to Cancer-related Molecular Pathways
Share to TGF-β signaling in diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15082782
DOI: 10.1128/mcb.24.9.3885-3893.2004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

p150Sal2 Is a p53-Independent Regulator of p21WAF1/CIPPMID 15082782Read ↗

Roles of SALL2 in tumorigenesis.Semantic proximity Read ↗

A tumor host range selection procedure identifies p150(sal2) as a target of polyoma virus large T antigen.Semantic proximity Read ↗

SALL2 represses cyclins D1 and E1 expression and restrains G1/S cell cycle transition and cancer-related phenotypes.Semantic proximity Read ↗

SUMO modification of Stra13 is required for repression of cyclin D1 expression and cellular growth arrest.Semantic proximity Read ↗

Tumor suppressor candidate TSSC5 is regulated by UbcH6 and a novel ubiquitin ligase RING105.Semantic proximity Read ↗

p53 is a NF-Y- and p21-independent, Sp1-dependent repressor of cyclin B1 transcription.Semantic proximity Read ↗

NM23-H1 tumor suppressor and its interacting partner STRAP activate p53 function.Semantic proximity Read ↗

LSD1 demethylase and the methyl-binding protein PHF20L1 prevent SET7 methyltransferase-dependent proteolysis of the stem-cell protein SOX2.Semantic proximity Read ↗

Effect of IPP5, a novel inhibitor of PP1, on apoptosis and the underlying mechanisms involved.Semantic proximity Read ↗

GAS41 is required for repression of the p53 tumor suppressor pathway during normal cellular proliferation.Semantic proximity Read ↗

The Atypical Cyclin-Like Protein Spy1 Overrides p53-Mediated Tumour Suppression and Promotes Susceptibility to Breast TumorigenesisSemantic proximity Read ↗

Api5 Contributes to E2F1 Control of the G1/S Cell Cycle Phase TransitionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.