Article
Immunogenetic analysis of post-schistosomal liver fibrosis.
Parasitology international - 1 Jun 2004
Hirayama Kenji
Abstract excerpt
Schistosomiasis is a major endemic parasitic disease in the world. In China, we have identified two major genes related to the severity of liver fibrosis, one an HLA class II gene, and the other the IL-13 gene. The frequency of the HLA-DRB5*0101 allele and that of the IL-13 promoter A/A (IL-13P- A/A) genotype were elevated in fibrotic patients, although the two genes are located on different chromosomes,...
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