Article
Genetic factors associated with development of cerebral malaria and fibrotic schistosomiasis.
The Korean journal of parasitology - 1 Dec 2002
Hirayama Kenji
Abstract excerpt
Collaborative studies have identified some genetic factors contributing to the development of severe forms of malaria and schistosomiasis. In Thailand, the TNF-alpha 5'-flanking region shows biallelic polymorphic sites at nucleotides -238, -308, -857, -863, and -1031, and seven alleles have been identified in patients from Myanmar. We found that the TNF promoter (TNFP)-D allele was significantly associated with...
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