MAPKAP1 rs10118570 polymorphism is associated with anti-infection and anti-hepatic fibrogenesis in schistosomiasis japonica.

doi:10.1371/journal.pone.0105995

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Article

MAPKAP1 rs10118570 polymorphism is associated with anti-infection and anti-hepatic fibrogenesis in schistosomiasis japonica.

PloS one - 1 Jan 2014

Zhu Xiao, Zhang Jinfang, Fan Wenguo, Gong Yunguo, Yan Jianhua, Yuan Zhidong, Wu Lang, Cui Hongjing, Luo Haiqing, Kong Qingming, Tang Li, Leng Shuilong, Liao Yufeng, Fu Weiming, Xiao Qin, Li Dongpei

Abstract excerpt

Chronic infection with Schistosoma japonicum is an important cause of hepatic fibrosis (HF). Human 9q33.3 is one of the most important loci for stress-related diseases. We examined the potential associations of 43 single-nucleotide polymorphisms (SNPs) with S. japonicum infection and HF in epidemic region in China. We identified a SNP (rs10118570 GG in mitogen-activated protein kinase associated protein 1,...

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PMID: 25153992
DOI: 10.1371/journal.pone.0105995
PMCID: PMC4143368

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MAPKAP1
ALB

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