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Article

Haplotype analysis of the apolipoprotein gene cluster on human chromosome 11.

Genomics - 1 May 2004

Olivier Michael, Wang Xujing, Cole Regina, Gau Brian, Kim Jessica, Rubin Edward M, Pennacchio Len A

Abstract excerpt

Members of the apolipoprotein gene cluster (APOA1/C3/A4/A5) on human chromosome 11q23 play an important role in lipid metabolism. Polymorphisms in both APOA5 and APOC3 are strongly associated with plasma triglyceride concentrations. The close genomic locations of these two genes as well as their functional similarity have hindered efforts to define whether each gene independently influences human triglyceride...

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Share to Apolipoproteins
Share to Chromosomes, Human, Pair 11
Share to APOA1 gene

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Linkage Disequilibrium

Share to Multigene Family

Share to Polymorphism, Single Nucleotide

Share to Recombination, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 15081120
DOI: 10.1016/j.ygeno.2003.11.016
PMCID: PMC2771640

Genes

APOA5
APOC3
APOA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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