Article
APOA1/C3/A5 haplotype and risk of hypertriglyceridemia in Taiwanese.
Clinica chimica acta; international journal of clinical chemistry - 1 Apr 2008
Chien Kuo-Liong, Fang Woei-Horng, Wen Hui-Chin, Lin Hsing-Pei, Lin Yen-Lin, Lin Shu-Wha, Wu June-Hsieh, Kao Jau-Tsuen
Abstract excerpt
BACKGROUND: Apolipoprotein A5 gene (APOA5) has been shown to modulate plasma triglyceride concentrations. We investigated 2 distinct APOA1/C3/A5 haplotypes roles for hypertriglyceridemia. METHODS: We recruited 308 cases of hypertriglyceridemia and 281 normal controls from a hospital. Twelve single nucleotide polymorphisms (SNPs) across the APOA1/C3/A5 gene region were genotyped. RESULTS: One haplotype containing...
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