Article
Genetic association study of APOA1/C3/A4/A5 gene cluster and haplotypes on triglyceride and HDL cholesterol in a community-based population.
Clinica chimica acta; international journal of clinical chemistry - 1 Feb 2008
Chien Kuo-Liong, Chen Ming-Fong, Hsu Hsiu-Ching, Su Ta-Chen, Chang Wei-Tien, Lee Chii-Ming, Lee Yuan-Teh
Abstract excerpt
BACKGROUND: Polymorphism of apolipoprotein A1/C3/A4/A5 gene cluster affected lipid profiles in general population. We reported 6 polymorphisms, APOA1 -75G>A, APOA1 83C>T, APOC3 3175C>G, APOC3 3206G>T, APOA4 127A>G, and APOA5 553G>T in APOA1/C3/A4/A5 gene and the haplotype structures on triglyceride and HDL traits among ethnic Chinese. RESULTS: Overall, there were statistically significant differences in the...
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