Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Angiotensin converting enzyme genotype influences the response to the angiotensin II receptor antagonist losartan in patients with hypertension.

Hypertension research : official journal of the Japanese Society of Hypertension - 1 Mar 2004

Nakamura Yasuyuki, Tamaki Shinji, Uchida Yasukazu, Ohmichi Nobuyuki, Yamaoka Osamu, Miyauchi Nobuo, Fukuhara Takehisa, Sayama Harumi, Yamada Tetsuhiro, Matsuo Shinro, Yamada Yutaka

Abstract excerpt

To examine whether the response to the angiotensin II receptor antagonist losartan varies depending on the angiotensin converting enzyme (ACE) genotype, we prospectively studied the effect of losartan in 42 hypertensive patients (20 men, 22 women; mean age: 60.4 years). After a 4-week observation...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Angiotensin Receptor Antagonists

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Antihypertensive Agents

Share to Blood Pressure

Share to Diastole

Share to Hypertension

Share to Losartan

Share to Peptidyl-Dipeptidase A

Source

Identifiers

PMID: 15080371
DOI: 10.1291/hypres.27.137

Genes

ACE
DBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15080371-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Angiotensin converting enzyme genotype influences the response to the angiotensin II receptor antagonist losartan in patients with hypertension.PMID 15080371Read ↗

Relationship between the response to the angiotensin converting enzyme inhibitor imidapril and the angiotensin converting enzyme genotype.Semantic proximity Read ↗

Relationship between polymorphism of the angiotensin-converting enzyme gene and the response to angiotensin-converting enzyme inhibition in hypertensive patients.Semantic proximity Read ↗

ACE genotype and ACE inhibitor response in kidney disease: a perspective.Semantic proximity Read ↗

Angiotensin-converting enzyme gene I/D genotype affected metoprolol-induced reduction in 24-hour average heart rate.Semantic proximity Read ↗

Angiotensin I-converting enzyme gene polymorphism and drug response.Semantic proximity Read ↗

Role of angiotensin converting enzyme genotype in sodium sensitivity in older hypertensives.Semantic proximity Read ↗

ACE (I/D) genotype as a predictor of the magnitude and duration of the response to an ACE inhibitor drug (enalaprilat) in humans.Semantic proximity Read ↗

Angiotensin-converting enzyme genotype interacts with systolic blood pressure to determine coronary heart disease risk in healthy middle-aged men.Semantic proximity Read ↗

Effect of angiotensin-converting enzyme genotype on renin-angiotensin components in hypertensives.Semantic proximity Read ↗

DD genotype of the angiotensin-converting enzyme gene is a risk factor for left ventricular hypertrophy.Semantic proximity Read ↗

Correlation of Angiotensin-converting enzyme gene polymorphism with effect of antihypertensive therapy by Angiotensin-converting enzyme inhibitor.Semantic proximity Read ↗

Renoprotective effects of losartan in diabetic nephropathy: interaction with ACE insertion/deletion genotype?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.